Compensatory Activation Of Cannabinoid CB2 Receptor Inhibition Of GABA Release In The Rostral Ventromedial Medulla In Inflammatory Pain

Pain (Chronic Non-Malignant)

Key Findings

Our data provide evidence that CB2 receptor function emerges in the RVM in persistent inflammation and that selective CB2 receptor agonists may be useful for treatment of persistent inflammatory pain.

Information and Links


Link: Compensatory Activation Of Cannabinoid CB2 Receptor Inhibition Of GABA Release In The Rostral Ventromedial Medulla In Inflammatory Pain

Year: 2017

DOI: 10.1523/JNEUROSCI.1310-16.2017.


Ratings

(How Ratings Work)

Pain (Chronic Non-Malignant) — 2


Possible to probable range of efficacy of cannabis for treatment of Pain (Chronic Non-Malignant) according to the results found in this study.

Drugs Used

WIN55212

SR144528

AM1241

GW405833

AM630