Local Enhancement Of Cannabinoid CB1 Receptor Signalling In The Dorsal Hippocampus Elicits An Antidepressant-like Effect

Depression

Key Findings

Enhanced CB1 activity in the hippocampus region of the brain produces an antidepressant-like effect.

Information and Links


Link: Local Enhancement Of Cannabinoid CB1 Receptor Signalling In The Dorsal Hippocampus Elicits An Antidepressant-like Effect

Year: 2007

DOI: 10.1097/FBP.0b013e3282ee7b44


Ratings

(How Ratings Work)

Depression — 2


Possible to probable range of efficacy of cannabis for treatment of Depression according to the results found in this study.

Drugs Used

HU210 (CB1 receptor agonist), URB597 (the fatty acid amide hydrolase inhibitor), AM251 (CB1 receptor antagonist)