A Chronic Low Dose Of Δ9-tetrahydrocannabinol (THC) Restores Cognitive Function In Old Mice

Aging

Key Findings

Here we show that a low dose of Δ9-tetrahydrocannabinol (THC) reversed the age-related decline in cognitive performance of mice aged 12 and 18 months. THC treatment restored hippocampal gene transcription patterns such that the expression profiles of THC-treated mice aged 12 months closely resembled those of THC-free animals aged 2 months. Thus, restoration of CB1 signaling in old individuals could be an effective strategy to treat age-related cognitive impairments.

Information and Links


Link: A Chronic Low Dose Of Δ9-tetrahydrocannabinol (THC) Restores Cognitive Function In Old Mice

Year: 2017

DOI: 10.1038/nm.4311


Ratings

(How Ratings Work)

Aging — 2


Possible to probable range of efficacy of cannabis for treatment of Aging according to the results found in this study.

Drugs Used

THC