Beta caryophyllene and caryophyllene oxide can induce apoptosis in lymphoma and neuroblastoma cells via modulation of 15-LOX (up-stream target) followed by the down-regulation of anti-apoptotic and up-regulation of pro-apoptotic genes.
Link: Beta Caryophyllene and Caryophyllene Oxide, Isolated from Aegle Marmelos, as the Potent Anti-inflammatory Agents against Lymphoma and Neuroblastoma Cells
Year: 2014
Possibility of efficacy for cannabis in treatment of Neuroblastoma according to the results found in this study.
Possibility of efficacy for cannabis in treatment of Cancer (Lymphoma) according to the results found in this study.
Beta caryophyllene and caryophyllene oxide