Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders

Dravet syndrome

Key Findings

CBD is anticonvulsant in many acute animal models, but there are limited data in chronic models. Accounts of dramatic improvements with cannabis-based productswith high CBD:D9-THC (e.g.,>20:1) ratios in the popularpress have sparked a serious interest among epilepsy clinicians in pursuing the rigorous, scientific study of CBD. Initial dose-tolerability and double-blind randomized, controlled studies focusingon target intractable epilepsy populations such as patients with Dravet and Lennox-Gastaut syndromes are being planned.

Information and Links


Link: Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders

Year: 2014

DOI: 10.1111/epi.12631


Ratings

(How Ratings Work)

Dravet syndrome — 3


Likely probability of the efficacy of cannabis for treatment of Dravet syndrome according to the results found in this study.

Drugs Used

CBD