Cannabinoid-2 Receptor Mediates Protection Against Hepatic Ischemia/reperfusion Injury

Hepatic Ischemia/Reperfusion Injury

Key Findings

These findings suggest that oxidative/nitrosative stress and inflammatory stimuli may trigger endocannabinoid production, and indicate that targeting CB2 cannabinoid receptors may represent a novel protective strategy against I/R injury.

Information and Links


Link: Cannabinoid-2 Receptor Mediates Protection Against Hepatic Ischemia/reperfusion Injury

Year: 2007

DOI: 10.1096/fj.06-7451com


Ratings

(How Ratings Work)

Hepatic Ischemia/Reperfusion Injury — 2


Possible to probable range of efficacy of cannabis for treatment of Hepatic Ischemia/Reperfusion Injury according to the results found in this study.

Drugs Used

Anandamide and 2-arachidonoylglycerol

JWH133