Cannabinoid Receptor 1 Blockade Ameliorates Albuminuria In Experimental Diabetic Nephropathy

Kidney Disease (Diabetic Nephropathy)

Key Findings

In experimental type 1 diabetes, the CB1 receptor is overexpressed by glomerular podocytes, and blockade of the CB1 receptor ameliorates albuminuria possibly via prevention of nephrin, podocin, and ZO-1 loss.

Information and Links


Link: Cannabinoid Receptor 1 Blockade Ameliorates Albuminuria In Experimental Diabetic Nephropathy

Year: 2010

DOI: 10.2337/db09-1336


Ratings

(How Ratings Work)

Kidney Disease (Diabetic Nephropathy) — 2


Possible to probable range of efficacy of cannabis for treatment of Kidney Disease (Diabetic Nephropathy) according to the results found in this study.

Drugs Used

AM251