Cannabinoids Inhibit Human Keratinocyte Proliferation Through A Non-CB1/CB2 Mechanism And Have A Potential Therapeutic Value In The Treatment Of Psoriasis

Key Findings

The cannabinoids tested (Delta-9-THC, CBN, CBD and CBG) all inhibited keratinocyte proliferation in a concentration-dependent manner. Our results show clearly that cannabinoids inhibit the proliferation of keratinocytes, thus demonstrating a therapeutic potential for the treatment of psoriasis, but further investigation is urgently needed to identify the mechanism by which they act in order to realise this potential.

Information and Links

Link: Cannabinoids Inhibit Human Keratinocyte Proliferation Through A Non-CB1/CB2 Mechanism And Have A Potential Therapeutic Value In The Treatment Of Psoriasis

Year: 2006

DOI: 10.1016/j.jdermsci.2006.10.009