Lou Gehrig’s disease or ALS is considered a chronic degenerative neurological illness associated with the selective loss of only those nerve cells needed for muscular motion located in the brain and spinal cord.
Amyotrophic, derived from ancient Greek, translates into no-muscle-nourishment, respectively. “Lateral” refers to muscles on either side of the affected nerve, and “sclerosis” means hardening. Without nourishment, a muscle wastes away and with it so does the ability to initiate movements.
Rated 2.5 / 5 (How Ratings Work)
Possible to probable range of efficacy of cannabis for treatment of amyotrophic lateral sclerosis (als or lou gehrig's disease).
Based on 14 Studies from 2001 - 2017
Study Name, Description & Year
Rating
Up-regulation Of CB2 Receptors In Reactive Astrocytes In Canine Degenerative Myelopathy, A Disease Model Of Amyotrophic Lateral Sclerosis
Animal study conducted on dogs — 2017
Neurological Aspects Of Medical Use Of Cannabidiol
Review/Meta-Analysis — 2017
Gingival Stromal Cells As An In Vitro Model: Cannabidiol Modulates Genes Linked With Amyotrophic Lateral Sclerosis
Laboratory Study — 2016
Cannabinoids In Neurodegenerative Disorders And Stroke/Brain Trauma: From Preclinical Models To Clinical Applications
Review — 2015
Tetrahydrocannabinol (THC) For Cramps In Amyotrophic Lateral Sclerosis: A Randomised, Double-blind Crossover Trial
27 ALS patients suffering from daily cramps — 2010
Cannabinoid Receptors And Endocannabinoids: Role In Neuroinflammatory And Neurodegenerative Disorders
Literature review — 2010
Increasing Cannabinoid Levels By Pharmacological And Genetic Manipulation Delay Disease Progression In SOD1 Mice
Animal study (mice) — 2006
Cannabinol Delays Symptom Onset In SOD1 (G93A) Transgenic Mice Without Affecting Survival
Mice — 2005
Survey Of Cannabis Use In Patients With Amyotrophic Lateral Sclerosis
131 ALS patients surveyed — 2004
Amyotrophic Lateral Sclerosis: Delayed Disease Progression In Mice By Treatment With A Cannabinoid.
Animal study (mice) — 2004
Marijuana In The Management Of Amyotrophic Lateral Sclerosis
A review of preclinical and anecdotal data — 2001