Melanin, produced by specialized skin cells (melanocytes), is the brownish pigment responsible for skin tone variants, as well as for the coloring that occurs in tanning, freckles, and moles. Exposure to UV light increases melanin production as a protective mechanism from excessive harmful rays.
Melanin converts the majority of UV light to harmless heat, preventing cellular mutation, thus protecting the skin from damage. The darker your skin, the greater your body’s protective ability. The majority of melanocytes lie in the base of the epidermis (outer skin layer).
While the majority of skin cancers are non-melanomas, melanomas make up the majority of deaths. Melanoma affects more Caucasians than other ethnicities. While direct sun exposure is healthy, natural and excessive sun exposure can contribute to mutation of DNA in melanocytes. The highest incidence of melanoma occurs in whites living in Australia.
Rated 1.3 / 5 (How Ratings Work)
Possibility of efficacy for cannabis in treatment of cancer of the skin (melanoma).
Based on 3 Studies from 2008 - 2015
Study Name, Description & Year
Rating
Exploiting Cannabinoid-induced Cytotoxic Autophagy To Drive Melanoma Cell Death
Animal study (mice) — 2015
Composition And In Vitro Anticancer Activities Of The Leaf Essential Oil Of Neolitsea Variabillima From Taiwan
Laboratory Study — 2013
Cannabinoid Receptor-1 Modulation Induces Apoptosis Of Human Melanoma Cells
Laboratory study on human melanoma cell lines — 2008