Schizophrenia remains one of the most common and serious yet least understood mental illnesses in the world today. Swiss psychiatrist Eugene Bleuler first used the word “schizophrenia” in 1911, which he derived from the Greek words schizo (to split) and phren (brain or mind).
However, unlike common usage suggests, it does not necessarily refer to a split personality(-ies) but rather a split or disconnect between thinking and feeling. Symptoms often include hallucinations involving the senses, making it difficult for patients to communicate or connect to others and the world.
Rated 3.2 / 5 (How Ratings Work)
Likely probability of the efficacy of cannabis for treatment of schizophrenia.
Based on 11 Studies from 2004 - 2017
Study Name, Description & Year
Rating
Improved Social Interaction, Recognition And Working Memory With Cannabidiol Treatment In A Prenatal Infection (poly I:C) Rat Model
Animal study (mice) — 2017
Plastic And Neuroprotective Mechanisms Involved In The Therapeutic Effects Of Cannabidiol In Psychiatric Disorders
Review — 2017
Cannabidiol Counteracts Amphetamine-Induced Neuronal And Behavioral Sensitization Of The Mesolimbic Dopamine Pathway Through A Novel MTOR/p70S6 Kinase Signaling Pathway
Animal study (rats) — 2016
ENDOCANNABINOID SYSTEM: A Multi-facet Therapeutic Target
Review — 2016
Cannabidiol Is A Partial Agonist At Dopamine D2High Receptors, Predicting Its Antipsychotic Clinical Dose
Animal study (rats) — 2016
Cannabidiol Enhances Anandamide Signaling And Alleviates Psychotic Symptoms Of Schizophrenia
A double-blind, randomized clinical trial of cannabidiol vs amisulpride conducted on 47 patients suffering from schizophrenia. — 2012
Consequences Of Cannabinoid And Monoaminergic System Disruption In A Mouse Model Of Autism Spectrum Disorders
Animal study (mice) — 2011
The Endocannabinoid System And Psychiatric Disorders
Meta-analysis — 2010
Uso Terapêutico Dos Canabinoides Em Psiquiatria [Therapeutical Use Of The Cannabinoids In Psychiatry]
Meta-analysis — 2010
S39-02 Antipsychotic Effects Of Cannabidiol
42 patients fulfilling DSM-IV criteria of acute paranoid schizophrenia — 2009
Cerebrospinal Anandamide Levels Are Elevated In Acute Schizophrenia And Are Inversely Correlated With Psychotic Symptoms
Antipsychotic-naive first-episode paranoid schizophrenics. — 2004