CB1 cannabinoid receptor ligands augment the antidepressant-like activity of biometals (magnesium and zinc) in the behavioural tests.

Depression

Key Findings

The simultaneous modulation of the cannabinoid system and supplementation of magnesium or zinc produce at least additive antidepressant-like effect.

Information and Links


Link: CB1 cannabinoid receptor ligands augment the antidepressant-like activity of biometals (magnesium and zinc) in the behavioural tests.

Year: 2018

DOI: 10.1111/jphp.12880


Ratings

(How Ratings Work)

Depression — 2


Possible to probable range of efficacy of cannabis for treatment of Depression according to the results found in this study.

Drugs Used

Oleamide, AM251, and biometals magnesium and zinc