Differential Effectiveness Of Selected Non-psychotropic Phytocannabinoids On Human Sebocyte Functions Implicates Their Introduction In Dry/seborrheic Skin And Acne Treatment

Acne Seborrhea

Key Findings

CBC and THCV suppressed sebaceous lipid synthesis, CBDV had only minor effects, whereas CBG and CBGV increased it. Importantly, CBC, CBDV and THCV significantly reduced arachidonic acid (AA)-induced "acne-like" lipogenesis. Moreover, THCV suppressed proliferation, and all phytocannabinoids exerted remarkable anti-inflammatory actions. Our data suggest that CBG and CBGV may have potential in the treatment of dry-skin syndrome, whereas CBC, CBDV and especially THCV show promise to become highly efficient, novel anti-acne agents.

Information and Links


Link: Differential Effectiveness Of Selected Non-psychotropic Phytocannabinoids On Human Sebocyte Functions Implicates Their Introduction In Dry/seborrheic Skin And Acne Treatment

Year: 2016

DOI: 10.1111/exd.13042


Ratings

(How Ratings Work)

Acne — 1


Possibility of efficacy for cannabis in treatment of Acne according to the results found in this study.

Seborrhea — 1


Possibility of efficacy for cannabis in treatment of Seborrhea according to the results found in this study.

Drugs Used

CBC

CBDV

CBG

CBGV

THCV