Effect Of Cannabinoid Receptor Agonists On Streptozotocin-induced Hyperalgesia In Diabetic Neuropathy

Diabetes Mellitus

Key Findings

CB1 & CB2 agonists reduce sensitivity to pain in a dose-dependent fashion, and COX-1 inhibitors (e.g., indomethacin) may increase these cannabinoid properties at low dosages.

Information and Links


Link: Effect Of Cannabinoid Receptor Agonists On Streptozotocin-induced Hyperalgesia In Diabetic Neuropathy

Year: 2008

DOI: 10.1159/000156485


Ratings

(How Ratings Work)

Diabetes Mellitus — 2


Possible to probable range of efficacy of cannabis for treatment of Diabetes Mellitus according to the results found in this study.

Drugs Used

CB-1 and CB-2 receptor agonists WIN55,212-2; Met-F-AEA; and AM1241