Endocannabinoid Modulation Of Orbitostriatal Circuits Gates Habit Formation

Alcohol Dependence / Abuse Obsessive-Compulsive Disorder (OCD)

Key Findings

Selective deletion of CB1 receptors in OFC-DS neurons prevents habit formation. Endocannabinoid-mediated weakening of goal-directed circuits allows for habit formation

Information and Links


Link: Endocannabinoid Modulation Of Orbitostriatal Circuits Gates Habit Formation

Year: 2016

DOI: 10.1016/j.neuron.2016.04.043


Ratings

(How Ratings Work)

Alcohol Dependence / Abuse — 2


Possible to probable range of efficacy of cannabis for treatment of Alcohol Dependence / Abuse according to the results found in this study.

Obsessive-Compulsive Disorder (OCD) — 2


Possible to probable range of efficacy of cannabis for treatment of Obsessive-Compulsive Disorder (OCD) according to the results found in this study.

Drugs Used

CB1 receptors