Endocannabinoid System Activation Contributes To Glucose Metabolism Disorders Of Hepatocytes And Promotes Hepatitis C Virus Replication

Hepatitis

Key Findings

HCV replication may not only increase the 2-AG content, but may also up-regulate the expression of CB1R of hepatocytes, then change the expression profile of glucose metabolism-related genes, thereby causing glucose metabolism disorders of hepatocytes and promoting HCV replication. Treatment with CB1R antagonist improved glucose metabolism disorders and inhibited viral genome replication.

Information and Links


Link: Endocannabinoid System Activation Contributes To Glucose Metabolism Disorders Of Hepatocytes And Promotes Hepatitis C Virus Replication

Year: 2014

DOI: 10.1016/j.ijid.2013.12.017


Ratings

(How Ratings Work)

Hepatitis — -1


No shown efficacy of cannabis for treatment of Hepatitis according to the results found in this study.

Drugs Used

CB1 receptors