Endocannabionoid System In Neurological Disorders

Parkinson's Disease Multiple Sclerosis (MS) Huntington's Disease Alzheimer's Disease

Key Findings

Despite different etiologies, neurodegenerative disorders exhibit similar mechanisms like neuro-inflammation, excitotoxicity, deregulation of intercellular communication, mitochondrial dysfunction and disruption of brain tissue homeostasis. Current treatments ameliorate the symptoms but are not curative. Interfering with the endocannabinoid signaling might be a valid therapeutic option in neuro-degeneration. CB1 and CB2 receptor signaling contributes to the control of Ca2+ homeostasis, trophic support, mitochondrial activity, and inflammatory conditions.

Information and Links


Link: Endocannabionoid System In Neurological Disorders

Year: 2016


Ratings

(How Ratings Work)

Parkinson's Disease — 3


Likely probability of the efficacy of cannabis for treatment of Parkinson's Disease according to the results found in this study.

Multiple Sclerosis (MS) — 3


Likely probability of the efficacy of cannabis for treatment of Multiple Sclerosis (MS) according to the results found in this study.

Huntington's Disease — 3


Likely probability of the efficacy of cannabis for treatment of Huntington's Disease according to the results found in this study.

Alzheimer's Disease — 3


Likely probability of the efficacy of cannabis for treatment of Alzheimer's Disease according to the results found in this study.

Drugs Used

Endocannabinoid system