The oral administration of beta-caryophyllene to rats significantly inhibited gastric mucosal injuries induced by necrotizing agents such as absolute ethanol and 0.6 N HCl. Thus, beta-caryophyllene elicited anti-inflammatory effects without any indication of gastric mucosal damage typical of non-steroidal anti-inflammatory agents.
Link: Gastric cytoprotection of the non-steroidal anti-inflammatory sesquiterpene, beta-caryophyllene.
Year: 1996
Possible to probable range of efficacy of cannabis for treatment of Gastro-Esophageal Reflux Disease (GERD) according to the results found in this study.
Beta-caryophyllene