Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves.

Post-Traumatic Stress Disorder Stress

Key Findings

These results suggest that activation of presynaptic CB1 receptors located on peripheral sympathetic nerve terminals mediate sympathoinhibitory effects in vitro and in vivo.

Information and Links


Link: Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB1 receptors on peripheral sympathetic nerves.

Year: 1996


Ratings

(How Ratings Work)

Post-Traumatic Stress Disorder — 2


Possible to probable range of efficacy of cannabis for treatment of Post-Traumatic Stress Disorder according to the results found in this study.

Stress — 2


Possible to probable range of efficacy of cannabis for treatment of Stress according to the results found in this study.

Drugs Used

Delta-9-THC

Anandamide (AEA)

CB1 antagonist, SR141716A