Inhibition Of Monoacylglycerol Lipase (MAGL) Enhances Cue-induced Reinstatement Of Nicotine-seeking Behavior In Mice

Addiction to Nicotine

Key Findings

The endocannabinoid system has been shown to control drug-seeking behaviors. This study implicates involvement of 2-AG in nicotine-seeking behaviors.

Information and Links


Link: Inhibition Of Monoacylglycerol Lipase (MAGL) Enhances Cue-induced Reinstatement Of Nicotine-seeking Behavior In Mice

Year: 2016

DOI: 10.1007/s00213-015-4117-5


Ratings

(How Ratings Work)

Addiction to Nicotine — 2


Possible to probable range of efficacy of cannabis for treatment of Addiction to Nicotine according to the results found in this study.

Drugs Used

Anandamide (AEA)

2-arachidonoylglycerol (2-AG)

Fatty acid amide hydrolase (FAAH)

Monoacylglycerol lipase (MAGL)