Potential Of The Cannabinoid CB(2) Receptor As A Pharmacological Target Against Inflammation In Parkinson's Disease

Parkinson's Disease

Key Findings

We have provided the first evidence on the up-regulation of CB2 receptors in glial elements in postmortem tissues of PD patients, which has been confirmed in an inflammatory model of this disease. In addition, we have provided evidence on the benefits derived from their activation in relation with the activation of microglial cells, the infiltration of macrophages and also certain capability of these cells to generate proinflammatory factors.

Information and Links


Link: Potential Of The Cannabinoid CB(2) Receptor As A Pharmacological Target Against Inflammation In Parkinson's Disease

Year: 2016

DOI: 10.1016/j.pnpbp.2015.03.017


Ratings

(How Ratings Work)

Parkinson's Disease — 2


Possible to probable range of efficacy of cannabis for treatment of Parkinson's Disease according to the results found in this study.

Drugs Used

CB2 receptors

HU-308