Synergy Between Delta9-tetrahydrocannabinol And Morphine In The Arthritic Rat

Addiction to Opiod Based Pain Killers Pain (Chronic Non-Malignant)

Key Findings

We have shown in past isobolographic studies that a small amount of Delta(9)-tetrahydrocannabinol (Delta(9)-THC) can enhance morphine antinociception in mice. The results of this new study indicated a synergistic interaction between Delta(9)-THC and morphine in both non-arthritic and the arthritic rats. As with acute preclinical pain models in which the Delta(9)-THC/morphine combination results in less tolerance development.

Information and Links


Link: Synergy Between Delta9-tetrahydrocannabinol And Morphine In The Arthritic Rat

Year: 2007


Ratings

(How Ratings Work)

Addiction to Opiod Based Pain Killers — 2


Possible to probable range of efficacy of cannabis for treatment of Addiction to Opiod Based Pain Killers according to the results found in this study.

Pain (Chronic Non-Malignant) — 2


Possible to probable range of efficacy of cannabis for treatment of Pain (Chronic Non-Malignant) according to the results found in this study.

Drugs Used

Delta-9-THC

Morphine