The Emerging Role Of The Endocannabinoid System In The Pathogenesis And Treatment Of Kidney Diseases

Kidney Disease (in General) Kidney Disease (Diabetic Nephropathy) Kidney Disease (Obesity-Related Kidney Dysfunction)

Key Findings

The ECB system is present in the kidney where it is involved in controlling various renal functions with important therapeutic implications. Increased CB1 receptor activity contributes to kidney hemodynamic abnormalities and dysfunction, whereas CB1 receptor blockade may attenuate and delay these changes. Additionally, non-psychoactive CB2 receptor agonists may offer therapeutic benefit in attenuating kidney injury and promoting tissue repair in DN- and obesity-induced renal damage.

Information and Links


Link: The Emerging Role Of The Endocannabinoid System In The Pathogenesis And Treatment Of Kidney Diseases

Year: 2016

DOI: 10.1515/jbcpp-2015-0055


Ratings

(How Ratings Work)

Kidney Disease (in General) — 3


Likely probability of the efficacy of cannabis for treatment of Kidney Disease (in General) according to the results found in this study.

Kidney Disease (Diabetic Nephropathy) — 3


Likely probability of the efficacy of cannabis for treatment of Kidney Disease (Diabetic Nephropathy) according to the results found in this study.

Kidney Disease (Obesity-Related Kidney Dysfunction) — 3


Likely probability of the efficacy of cannabis for treatment of Kidney Disease (Obesity-Related Kidney Dysfunction) according to the results found in this study.

Drugs Used

Endocannabinoids