Toll-like receptors (TLRs) are the sensors of pathogen-associated molecules that trigger tailored innate immune intracellular signalling responses to initiate innate immune reactions. Data from human studies indicate that complex interplay exists between TLR signalling and Multiple Sclerosis (MS) pathogenesis.
Link: Toll-like Receptor Signalling As A Cannabinoid Target In Multiple Sclerosis
Year: 2017
DOI: 10.1016/j.neuropharm.2016.04.009
Likely probability of the efficacy of cannabis for treatment of Multiple Sclerosis (MS) according to the results found in this study.
Cannabinoids
Sativex