Care By Design, a California cannabis production company, just released the findings from a patient survey, giving the community some insight into the efficacy of cannabis. The survey ultimately compared answers from 621 unique California patients using THC and CBD to alleviate their medical conditions.

The report “represents preliminary data based on less than one thousand patients. It is not meant to prove patients with guidance on dosing or medical treatment. Rather, it is meant to suggest possible areas for additional research.

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The Care By Design survey took place over a six month period, between March and August of 2015. Patients who had been using cannabis for over 30 days were asked about their conditions, the THC:CBD ratios they were using, and the overall impact of CBD-rich cannabis therapy on pain, discomfort, mood, energy, and overall wellbeing. Care By Design is continuing to compile patient surveys in order to provide more support for further cannabis research.


While this study only captures 621 sets of patient responses, it is an incredibly valuable effort that gives more credence to the anecdotal evidence that the cannabis community has had to rely on for legitimacy.

Hopefully, the key findings of this report inspire government agencies to conduct more substantial studies on the effectiveness of cannabis. Smoke Reports will provide updates and more information on the medical effectiveness of cannabis as more studies are released.

Key Findings from Patient Survey

  1. Cannabis patients use CBD-rich cannabis medicine to provide relief for a variety of diseases and conditions.
  2. There is no correlation between a specific condition and the most effective ratio of THC to CBD. It did appear that issues with the central nervous system responded better to CBD-dominant therapies, while pain and inflammation favored more equal levels of THC and CBD.
  3. CBD alone is not as effective as a ratio of THC to CBD that makes the patient comfortable.
  4. CBD-dominant cannabis appears to be good at relieving pain, particularly with fibromyalgia, headaches and migraines.
  5. CBD-rich cannabis appears to be effective with a sense of wellbeing, particularly for PTSD.
  6. CBD-rich cannabis does not appear to impact energy levels.
  7. The only group who reported feeling a decreased sense of wellbeing or a worsening of mood were those who were using CBD-rich medicine only for wellbeing, suggesting that CBD products “may not be appropriate as a supplement for people who are otherwise healthy.”

Conditions Surveyed

Percentage of Reporting Patients by Condition

  • 21.4% for mood or psychiatric disorders
  • 19.4% for inflammatory conditions
  • 13.7% for conditions marked by pain
  • 12.4% for diseases of and injures to the central nervous system
  • 12.1% to treat cancer-related symptoms
  • 21% for general wellbeing/unspecified

Findings for Wellbeing, Pain, Mood, and Energy

The majority of the 621 patients surveyed (88.2%) stated that CBD-rich cannabis therapy improved their overall wellbeing, with the greatest improvements reported by patients suffering from PTSD and anxiety.


Nearly three quarters of the patients surveyed (72.6%) reported a decrease in pain or discomfort. All of the patients with headaches, migraines, fibromyalgia, irritable bowel syndrome, and spinal cord injuries reported a decrease in pain or discomfort. Fewer than 1% of all patients surveyed reported an increase in pain after using CBD-rich cannabis medicine, and these were all patients treating ALS.

Nearly two-thirds of patients surveyed (64.2%) stated that CBD-rich cannabis improved their mood. All of the patients (100%) with PTSD and spinal cord injuries reported improvement in mood. A small group of patients with sleep problems and cancer reported a worsening of mood after at least 30 days of cannabis therapy (2% total).

Mykayla had T-cell acute lymphoblastic leukemia

Mykayla Uses Cannabis to Treat T-cell Acute Lymphoblastic Leukemia

When it comes to energy levels after using CBD-rich medicine, half of patients (50.4%) reported no change in energy levels. The most likely to report reduced energy levels after administering cannabis medicine were those patients suffering from headaches or migraines. Overall, 11% of patients said they felt less energetic from undergoing cannabis therapies.

Cannabis Ratios

Care By Design creates a line of cannabis medicine that is accurately dosed to contain consistent quantities of THC and CBD. One very interesting finding of this survey was that 42.3% of patients do not know what ratios of THC to CBD they are ingesting.

While there is no direct correlation between a specific condition and the effectiveness of a specific THC:CBD ratio, some trends are slowly emerging. Still, it is alarming that cannabis patients are unaware of the medicine they are taking, as measured dosing is the best way to determine what is working for an individual patient.

Cannabis Medicine Designed with Ratios in Mind

Care By Design: Cannabis Medicine Created with Ratios in Mind

Moving Forward

Care By Design will continue to collect survey responses so that future reports of cannabis effectiveness can be published in a timely manner. While this report reveals some valuable cannabis information, it is important to remember that these findings are meant to promote additional research, and should not be used as medical guidance for treating a serious condition.

Further Research is Needed to Free Medical Cannabis from Prohibition

Further Research is Needed to Free Medical Cannabis from Prohibition

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